Microbiota: dual-faceted player in experimental colitis.

@article{Feng2010MicrobiotaDP,
  title={Microbiota: dual-faceted player in experimental colitis.},
  author={Ting Feng and Charles O Elson and Yingzi Cong},
  journal={Gut microbes},
  year={2010},
  volume={1 6},
  pages={388-91}
}
We have recently demonstrated that microbiota stimulation of innate immune pathways is required for T cell spontaneous proliferation and chronic intestinal inflammation. Microbiota promoted spontaneous proliferation of T cells by activating dendritic cells to produce interleukin (IL)-6 via a TLR/Myd88-dependent pathway. Although both CBir1-specific Tcr… CONTINUE READING