Microbiological aspects in the hydroxylation of estrogens by Fusarium moniliforme.


A strain of Fusarium moniliforme (IH4), isolated from soil, showed outstanding enzymatic abilities to hydroxylate a number of estrogens. Estrone and estradiol were transformed into the 15alpha-hydroxy derivatives, and estradiol 3-methyl ether was transformed into the corresponding 6beta-hydroxy derivative. Delta(6)-Estrone was not hydroxylated. The… (More)


10 Figures and Tables

Slides referencing similar topics