Microbicides and other topical strategies to prevent vaginal transmission of HIV

@article{Lederman2006MicrobicidesAO,
  title={Microbicides and other topical strategies to prevent vaginal transmission of HIV},
  author={M. Lederman and R. Offord and O. Hartley},
  journal={Nature Reviews Immunology},
  year={2006},
  volume={6},
  pages={371-382}
}
The HIV epidemic is, by many criteria, the worst outbreak of infectious disease in history. The rate of new infections is now ∼5 million per year, mainly in the developing world, and is increasing. Women are now substantially more at risk of infection with HIV than men. With no cure or effective vaccine in sight, a huge effort is required to develop topical agents (often called microbicides) that, applied to the vaginal mucosa, would prevent infection of these high-risk individuals. We discuss… Expand
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