Microbial view of central nervous system autoimmunity

@article{Berer2014MicrobialVO,
  title={Microbial view of central nervous system autoimmunity},
  author={K. Berer and G. Krishnamoorthy},
  journal={FEBS Letters},
  year={2014},
  volume={588}
}
  • K. Berer, G. Krishnamoorthy
  • Published 2014
  • Biology, Medicine
  • FEBS Letters
  • Not much is known about the initial events leading to the development of the central nervous system (CNS)‐specific autoimmune disorder Multiple Sclerosis (MS). Environmental factors are suspected to trigger the pathogenic events in people with genetic disease susceptibility. Historically, many infectious microbes were linked to MS, but no infection has ever been demonstrated to be the cause of the disease. Recent emerging evidence from animal models of MS suggests a causal link with resident… CONTINUE READING
    98 Citations
    The Gut–CNS Axis in Multiple Sclerosis
    • 1
    Mucosal-Associated Invariant T Cells in Multiple Sclerosis: The Jury is Still Out
    • 28
    • PDF
    Multiple Sclerosis and T Lymphocytes: An Entangled Story
    • 93
    • Highly Influenced
    • PDF
    Environmental Factors and Their Regulation of Immunity in Multiple Sclerosis
    • 25
    [Autoimmune Diseases of the Nervous System: Problem Statement and Prospects].
    • 1
    • PDF
    Corrigendum to ‘Multiple sclerosis: New insights and trends’
    • 2
    • PDF
    Does the Gut Microbiota Influence Immunity and Inflammation in Multiple Sclerosis Pathophysiology?
    • 23
    • PDF
    T cell responses in the central nervous system
    • 104
    • PDF
    Environmental factors in multiple sclerosis.
    • 10

    References

    SHOWING 1-10 OF 102 REFERENCES
    Remote control-triggering of brain autoimmune disease in the gut.
    • 31
    New immunopathologic insights into multiple sclerosis
    • 28
    Commensal gut flora and brain autoimmunity: a love or hate affair?
    • 67
    • PDF
    Revisiting the old link between infection and autoimmune disease with commensals and T helper 17 cells
    • 25
    Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
    • 833
    • PDF
    Molecular Mimicry, Bystander Activation, or Viral Persistence: Infections and Autoimmune Disease
    • 439
    • PDF
    Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis
    • 789
    • PDF
    TLR-dependent T cell activation in autoimmunity
    • K. Mills
    • Biology, Medicine
    • Nature Reviews Immunology
    • 2011
    • 370
    • PDF
    Experimental models of spontaneous autoimmune disease in the central nervous system
    • 41
    Proinflammatory Bacterial Peptidoglycan as a Cofactor for the Development of Central Nervous System Autoimmune Disease
    • 106
    • Highly Influential
    • PDF