Microbial transformation of sterols to C19-steroids by Rhodococcus equi.

  title={Microbial transformation of sterols to C19-steroids by Rhodococcus equi.},
  author={S Ahmad and Prodyut K. Roy and Abdul Wahab Khan and Siddharhta Basu and Bhavdish Narayan Johri},
  journal={World journal of microbiology & biotechnology},
  volume={7 5},
A wild-type strain of Rhodococcus equi, isolated from soil, degraded cholesterol, β-sitosterol, stigmasterol and mixed sterois to androst-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD). A definite preference for a relatively simply structured cholesterol side chain was observed. Highest specific cholesterol side-chain cleavage was associated with active growth of the culture. Maximum yield of ADD was obtained when sodium acetate and cholesterol were incorporated together in the… CONTINUE READING
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