Microbial transformation of nitriles to high-value acids or amides.

@article{Chen2009MicrobialTO,
  title={Microbial transformation of nitriles to high-value acids or amides.},
  author={Jing Chao Chen and Ren-Chao Zheng and Yuguo Zheng and Yin-Chu Shen},
  journal={Advances in biochemical engineering/biotechnology},
  year={2009},
  volume={113},
  pages={33-77}
}
Biotransformation of nitriles mediated by nitrile-amide converting enzymes has attracted considerable attention and developed tremendously in the recent years in China since it offers a valuable alternative to traditional chemical reaction which requires harsh conditions. As a result, an upsurge of these promising enzymes (including nitrile hydratase, nitrilase and amidase) has been taking place. This review aims at describing these enzymes in detail. A variety of microorganisms harboring… CONTINUE READING
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