Microbial subversion of heparan sulfate proteoglycans.

  title={Microbial subversion of heparan sulfate proteoglycans.},
  author={Ye Hong Chen and Martin G{\"o}tte and Jian Liu and Pyong Woo Park},
  journal={Molecules and cells},
  volume={26 5},
The interactions between the host and microbial pathogen largely dictate the onset, progression, and outcome of infectious diseases. Pathogens subvert host components to promote their pathogenesis and, among these, cell surface heparan sulfate proteoglycans are exploited by many pathogens for their initial attachment and subsequent cellular entry. The ability to interact with heparan sulfate proteoglycans is widespread among viruses, bacteria, and parasites. Certain pathogens also use heparan… CONTINUE READING


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Highly Influential
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