Microbial production of propionic acid from propionibacteria: Current state, challenges and perspectives

@article{Liu2012MicrobialPO,
  title={Microbial production of propionic acid from propionibacteria: Current state, challenges and perspectives},
  author={Long Liu and Yunfeng Zhu and Jianghua Li and Miao Wang and Pengsoon Lee and Guocheng Du and Jian Chen},
  journal={Critical Reviews in Biotechnology},
  year={2012},
  volume={32},
  pages={374 - 381}
}
Propionic acid (PA) is an important building block chemical and finds a variety of applications in organic synthesis, food, feeding stuffs, perfume, paint and pharmaceutical industries. Presently, PA is mainly produced by petrochemical route. With the continuous increase in oil prices, public concern about environmental pollution, and the consumers’ desire for bio-based natural and green ingredients in foods and pharmaceuticals, PA production from propionibacteria has attracted considerable… 
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77 Citations
Highly Influential Citations
7
Background Citations
31
Methods Citations
3

77 Citations

Fermentative production of propionic acid: prospects and limitations of microorganisms and substrates.

TLDR
Fermentative propionic acid production emerges as competitor to chemical synthesis and a wide range of substrates employed in propionic Acid fermentation is analyzed with particular interest in the prospects of inexpensive renewable feedstocks to produce cost-competitive bio-propionic acid.

Microbial Propionic Acid Production

TLDR
The current review provides an in-depth description of the major metabolic routes for propionate production from an energy optimization perspective and suggests ways in which the target yield, productivity and titre can be achieved.

An overview of biotechnological production of propionic acid: From upstream to downstream processes

Propionic Acid: Method of Production, Current State and Perspectives

TLDR
A comprehensive synthesis and review of important biotechnological aspects of propionic acid production as a common ingredient in food and biotechnology industries and put forward strategies for overcoming the limitations of competitive microbial production from the economical point of view.

Current advances in biological production of propionic acid

TLDR
This review provides a comprehensive overview of important biotechnological aspects of propionic acid production using recent technologies such as employment of co-culture, genetic and metabolic engineering, immobilization technique and efficient bioreactor systems.

Propionic acid production by Propionibacterium freudenreichii using sweet sorghum bagasse hydrolysate.

TLDR
Compared to glucose (this study) and hydrolysates from other biomass species (literature), use of SSB hydrolysate as a renewable glucose source resulted in comparable or even higher propionic acid yields.

Microbial Production of Short Chain Fatty Acids from Lignocellulosic Biomass: Current Processes and Market

TLDR
The aim of the present review is to summarize recent research and development of short chain fatty acids production by anaerobic fermentation of nonfood biomass and to evaluate the status and outlook for a sustainable industrial production of such biochemicals.

Engineering propionibacteria as versatile cell factories for the production of industrially important chemicals: advances, challenges, and prospects

TLDR
This review introduces the major species of propionibacteria and their properties and provides an overview of their functions and applications, and discusses advances in the genome sequencing and metabolic engineering of these bacteria.

Propionate Production by Bioelectrochemically-Assisted Lactate Fermentation and Simultaneous CO2 Recycling

TLDR
Electrofermentation in a two-chamber cell can be applied to control lactate fermentation toward propionate production and to recycle the resulting CO2 into acetate, increasing the VFA yield and avoiding carbon emissions and addition of chemicals for pH control.

Genome-scale model guided design of Propionibacterium for enhanced propionic acid production

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References

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TLDR
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