Microbial process for preparation of optically active 3-hydroxypyrrolidine derivatives

@inproceedings{2001MicrobialPF,
  title={Microbial process for preparation of optically active 3-hydroxypyrrolidine derivatives},
  author={웡존윙},
  year={2001}
}
PURPOSE: Provided is a process that comprises contacting pyrrolidine-1-carboxylic acid phenylester with a suitable microorganism capable of hydroxylating it, and recovering the optically active 3-hydroxypyrrolidine derivatives that are selectively formed and accumulated. CONSTITUTION: The process for the production of a compound of the formula(2) from a compound of the formula(1) comprises hydroxylating a compound of the formula(1) in the presence of at least one hydroxylating enzyme produced… CONTINUE READING

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