Microbial photoinactivation by 470 nm radiation: an investigation into the underlying photobiological mechanism

@inproceedings{Hoenes2018MicrobialPB,
  title={Microbial photoinactivation by 470 nm radiation: an investigation into the underlying photobiological mechanism},
  author={Katharina Hoenes and Kerstin Wild and Julian Schmid and Barbara Spellerberg and Martin Hessling},
  booktitle={BiOS},
  year={2018}
}
The photoinactivation properties of 405 (violet) and 470 nm (blue) light have been studied by many research groups within the last few years. Both wavelengths are capable of disinfecting bacteria and fungi, with 405 nm radiation being more efficient. The basic photoinactivation mechanism is understood for 405 nm. Violet light is absorbed by endogenous porphyrins that act as photosensitizers and generate reactive oxygen species, subsequently destroying the microorganisms from within. The… 
405 nm and 450 nm Photoinactivation of Saccharomyces cerevisiae
TLDR
The results are compatible with photoinactivated Saccharomyces cerevisiae cells being in a viable but nonculturable state, and arguing against the previously suspected mechanism of cell membrane damage during photoinactivation with visible light at least for the investigated strain.

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