Microbial genotype–phenotype mapping by class association rule mining

  title={Microbial genotype–phenotype mapping by class association rule mining},
  author={Makio Tamura and Patrik D'haeseleer},
MOTIVATION Microbial phenotypes are typically due to the concerted action of multiple gene functions, yet the presence of each gene may have only a weak correlation with the observed phenotype. Hence, it may be more appropriate to examine co-occurrence between sets of genes and a phenotype (multiple-to-one) instead of pairwise relations between a single gene and the phenotype. Here, we propose an efficient class association rule mining algorithm, netCAR, in order to extract sets of COGs… CONTINUE READING
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