Microbial generation of nocathiacin acid from nocathiacin I.

  title={Microbial generation of nocathiacin acid from nocathiacin I.},
  author={Maochen Wei and Shuzhen Wang and Yongliang Fang and Yijun Chen},
  journal={Bioresource technology},
  volume={101 10},
Microbial generation of nocathiacin acid from nocathiacin I by manipulating enzymatic activities related to C-terminal dehydroalanine hydrolysis in Amycolatopsis fastidiosa LCB1001 was investigated by comparing the effects of various factors including metal ions, amino acid precursors and starting pH on the transformation. CuCl(2) and cysteine significantly increased bioconversion yields, and starting pH and time were also major factors affecting the product yield. Under optimal conditions, the… Expand
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