Microbial dark matter ecogenomics reveals complex synergistic networks in a methanogenic bioreactor

@article{Nobu2015MicrobialDM,
  title={Microbial dark matter ecogenomics reveals complex synergistic networks in a methanogenic bioreactor},
  author={Masaru Konishi Nobu and Takashi Narihiro and Christian Rinke and Yoichi Kamagata and Susannah G. Tringe and Tanja Woyke and Wen-Tso Liu},
  journal={The ISME Journal},
  year={2015},
  volume={9},
  pages={1710-1722}
}
Ecogenomic investigation of a methanogenic bioreactor degrading terephthalate (TA) allowed elucidation of complex synergistic networks of uncultivated microorganisms, including those from candidate phyla with no cultivated representatives. Our previous metagenomic investigation proposed that Pelotomaculum and methanogens may interact with uncultivated organisms to degrade TA; however, many members of the community remained unaddressed because of past technological limitations. In further… 
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