Microbial contamination of hematopoietic progenitor cell grafts-incidence, clinical outcome, and cost-effectiveness: an analysis of 735 grafts.

@article{Kamble2005MicrobialCO,
  title={Microbial contamination of hematopoietic progenitor cell grafts-incidence, clinical outcome, and cost-effectiveness: an analysis of 735 grafts.},
  author={Rammurti T. Kamble and Shubham Pant and George B. Selby and Mohamed A Kharfan-Dabaja and Sanjay Sethi and Kristen Kratochvil and Nancy Kohrt and Howard Ozer},
  journal={Transfusion},
  year={2005},
  volume={45 6},
  pages={874-8}
}
BACKGROUND Screening of progenitor cell grafts (marrow, peripheral blood, and cord blood) for microbial contamination is required by the standards of AABB. Clinical sequelae from infusion of these contaminated grafts, however, is uncommon. STUDY DESIGN AND METHODS A retrospective analysis of 735 consecutive marrow and peripheral blood progenitor cell harvests between 1998 and 2003 was performed. Analysis included incidence, clinical outcome, and cost outcomes of positive blood cultures and… CONTINUE READING

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