Microbial antigens mediate HLA-B27 diseases via TLRs.

@article{Pllnen2009MicrobialAM,
  title={Microbial antigens mediate HLA-B27 diseases via TLRs.},
  author={Raimo P{\"o}ll{\"a}nen and Tarvo Sillat and Jukka Sakari Pajarinen and Jaakko Lev{\'o}n and Emilia Kaivosoja and Yrj{\"o} T. Konttinen},
  journal={Journal of autoimmunity},
  year={2009},
  volume={32 3-4},
  pages={
          172-7
        }
}
HLA-B27 positive individuals are predisposed to reactive arthritis developing 1-3 weeks after urogenital and gastrointestinal infections. Also ankylosing spondylitis (AS) associates strongly to HLA-B27, but no specific infection, Klebsiella pneumoniae excluded, has been linked to it. Before the discovery of its HLA-B27 association there were many reports suggesting a link between chronic prostatitis in men or pelvic inflammatory disease in women and AS. They have since been forgotten although… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 18 CITATIONS

Bone responses in health and infectious diseases: A focus on osteoblasts.

  • The Journal of infection
  • 2017
VIEW 8 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED