Microbial Production of Glyceric Acid, an Organic Acid That Can Be Mass Produced from Glycerol

@article{Habe2009MicrobialPO,
  title={Microbial Production of Glyceric Acid, an Organic Acid That Can Be Mass Produced from Glycerol},
  author={Hiroshi Habe and Yuko Shimada and Toshiharu Yakushi and Hiromi Hattori and Yoshitaka Ano and Tokuma Fukuoka and Dai Kitamoto and Masayuki Itagaki and Kunihiro Watanabe and Hiroshi Yanagishita and Kazunobu Matsushita and Keiji Sakaki},
  journal={Applied and Environmental Microbiology},
  year={2009},
  volume={75},
  pages={7760 - 7766}
}
ABSTRACT Glyceric acid (GA), an unfamiliar biotechnological product, is currently produced as a small by-product of dihydroxyacetone production from glycerol by Gluconobacter oxydans. We developed a method for the efficient biotechnological production of GA as a target compound for new surplus glycerol applications in the biodiesel and oleochemical industries. We investigated the ability of 162 acetic acid bacterial strains to produce GA from glycerol and found that the patterns of productivity… Expand
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TLDR
Results strongly suggest that the observed decrease in GA production by Gluconobacter spp. Expand
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TLDR
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TLDR
The enantiomeric excess of the GA produced was revealed to be 44%, indicating that this strain converted glycerol to d-GA with a lower enantioselectivity than other acetic acid bacteria, which had 70-99% ee. Expand
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TLDR
This work proposes a novel approach that allows higher productivities, cleaner production, and reduction in water and energy consumption, and demonstrates the applicability of the proposed approach. Expand
Expression and characterization of a class III alcohol dehydrogenase gene from Gluconobacter frateurii in the presence of methanol during glyceric acid production from glycerol.
TLDR
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TECHNOLOGIES OF SYNTHESIS OF ORGANIC SUBSTANCES BY MICROORGANISMS USING WASTE BIODIESEL PRODUCTION
TLDR
Using of crude glycerol as a substrate will reduce the cost of products of microbial synthesis and increase the profitability of biodiesel production. Expand
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TLDR
The successful production of d-glyceric acid based on glycerol via glyceraldehyde in a two-step enzyme reaction with the FAD-dependent alditol oxidase from Streptomyces coelicolor A3(2) is demonstrated. Expand
Optimization of 1,3-dihydroxyacetone production from crude glycerol by immobilized Gluconobacter oxydans MTCC 904.
TLDR
It is established that proper optimization of fermentation medium reduces the adverse effect of impurities in crude glycerol on fermentation process and DHA yield. Expand
Potential Role of Halophile in Crude Glycerol Based Biorefinery
Biorefinery includes microbial fermentation processes which could utilize glycerol as raw material for the production of bio-derived building block compounds and polymers. The recent expansion inExpand
Disruption of the Membrane-Bound Alcohol Dehydrogenase-Encoding Gene Improved Glycerol Use and Dihydroxyacetone Productivity in Gluconobacter oxydans
TLDR
It was discovered that the G. oxydans mutant ΔadhA, in which the membrane-bound alcohol dehydrogenase-encoding gene (adhA) was disrupted, significantly improved its ability to grow in a higher concentration of glycerol and to produce DHA compared to a wild-type strain. Expand
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