Microbial Metabolism of Carbamates Ii

The inhibition of hexokinase (Meyerhof and Wilson, 1948), choline oxidase (Goldfinger et al., 1947), and other enzyme systems by urethan and related carbamates has been studied extensively. Yet precisely how these compounds exert their physiological effects is unknown. Warburg (1921) considered urethan to be an "indifferent" narcotic, blocking… CONTINUE READING