Microbial Genes in the Human Genome: Lateral Transfer or Gene Loss?

@article{Salzberg2001MicrobialGI,
  title={Microbial Genes in the Human Genome: Lateral Transfer or Gene Loss?},
  author={S. Salzberg and O. White and J. Peterson and J. Eisen},
  journal={Science},
  year={2001},
  volume={292},
  pages={1903 - 1906}
}
The human genome was analyzed for evidence that genes had been laterally transferred into the genome from prokaryotic organisms. Protein sequence comparisons of the proteomes of human, fruit fly, nematode worm, yeast, mustard weed, eukaryotic parasites, and all completed prokaryote genomes were performed, and all genes shared between human and each of the other groups of organisms were collected. About 40 genes were found to be exclusively shared by humans and bacteria and are candidate… Expand
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