Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function

@article{Olszak2012MicrobialED,
  title={Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function},
  author={Torsten Olszak and Dingding An and Sebastian Zeissig and Miguel Pinilla Vera and Julia Richter and Andr{\'e} Franke and Jonathan N. Glickman and Reiner Siebert and Rebecca Marlene Baron and Dennis L. Kasper and Richard S. Blumberg},
  journal={Science},
  year={2012},
  volume={336},
  pages={489 - 493}
}
Microbes: Early and Often Epidemiological studies have suggested that the increase in the incidence of asthma and other inflammatory diseases seen in many parts of the world may be due to a reduced exposure to microbes during early childhood. Olszak et al. (p. 489, published online 22 March) now show that commensal microflora help to regulate the numbers and functions of natural killer T (NKT) cells in the colon and lung in mice. Germ-free mice had elevated numbers of NKT cells in these tissues… 
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