Microbial Diversity of Genital Ulcer Disease in Men Enrolled in a Randomized Trial of Male Circumcision in Kisumu, Kenya

@inproceedings{Mehta2012MicrobialDO,
  title={Microbial Diversity of Genital Ulcer Disease in Men Enrolled in a Randomized Trial of Male Circumcision in Kisumu, Kenya},
  author={Supriya D. Mehta and Stefan J Green and Ian Maclean and Hong Jie Hu and Robert C Bailey and P. M. Gillevet and Greg T. Spear},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND Medical male circumcision (MMC) reduces the risk of genital ulcer disease (GUD) in men by 50%. In Ugandan and Kenyan trials, a sexually transmissible agent was not identified in 50-60% of GUD specimens by polymerase chain reaction (PCR) assay. We sought to better define the etiology of GUD in men participating in the Kenyan trial and examine how MMC affects GUD etiology. METHODS We defined GUD of unknown etiology as negative for HSV (type 1 and type 2), T. pallidum, and H. ducreyi… CONTINUE READING
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The protective effect of medical male circumcision against HIV is not mediated by reduction in HSV-2: Results from the randomized trial of MMC to reduce HIV in Kisumu, Kenya

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