Microbial Composition Predicts Genital Tract Inflammation and Persistent Bacterial Vaginosis in South African Adolescent Females.

Abstract

Young African females are at an increased risk of HIV acquisition, and genital inflammation or the vaginal microbiome may contribute to this risk. We studied these factors in 168 HIV-negative South African adolescent females aged 16 to 22 years. Unsupervised clustering of 16S rRNA gene sequences revealed three clusters (subtypes), one of which was strongly… (More)
DOI: 10.1128/IAI.00410-17

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Cite this paper

@article{Lennard2018MicrobialCP, title={Microbial Composition Predicts Genital Tract Inflammation and Persistent Bacterial Vaginosis in South African Adolescent Females.}, author={Katie S Lennard and Smritee Dabee and Shaun L Barnabas and Enock Havyarimana and A J C Blakney and Shameem Z. Jaumdally and Gerrit Botha and Nonhlanhla N. Mkhize and Linda-Gail Bekker and David Allan Lewis and Glenda Gray and Nicola Mulder and Jo-Ann S Passmore and Heather B. Jaspan}, journal={Infection and immunity}, year={2018}, volume={86 1} }