Microbe-dendritic cell dialog controls regulatory T-cell fate.

  title={Microbe-dendritic cell dialog controls regulatory T-cell fate.},
  author={John R Grainger and Jason Andrew Hall and Nicolas Bouladoux and Guillaume Oldenhove and Yasmine Belkaid},
  journal={Immunological reviews},
  volume={234 1},
Each microenvironment is controlled by a specific set of regulatory elements that have to be finely and constantly tuned to maintain local homeostasis. These environments could be site specific, such as the gut environment, or induced by chronic exposure to microbes. Various populations of dendritic cells are central to the orchestration of this control. In this review, we discuss some new findings associating dendritic cells from defined compartments with the induction and control of… CONTINUE READING

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