Microautoradiographic study for the differentiation of intratumoral macrophages, granulation tissues and cancer cells by the dynamics of fluorine-18-fluorodeoxyglucose uptake.

@article{Kubota1994MicroautoradiographicSF,
  title={Microautoradiographic study for the differentiation of intratumoral macrophages, granulation tissues and cancer cells by the dynamics of fluorine-18-fluorodeoxyglucose uptake.},
  author={Ryo Kubota and Kazuo Kubota and Shogo Yamada and Masao Tada and Tatsuo Ido and Nobuaki Tamahashi},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1994},
  volume={35 1},
  pages={104-12}
}
UNLABELLED A substantial amount of macrophage infiltration occurs in both human and animal tumors. We previously showed that 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) uptake was higher in tumor-associated macrophages and young granulation tissues than in tumor cells. Differentiation of intratumoral non-neoplastic cells from neoplastic cells is important not only for the reduction of false-positives in FDG-PET tumor studies but also for patient management. METHODS A time-course study was… CONTINUE READING
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