Microaspiration in intubated critically ill patients: diagnosis and prevention.

@article{Nseir2011MicroaspirationII,
  title={Microaspiration in intubated critically ill patients: diagnosis and prevention.},
  author={Saad Nseir and Farid Zerimech and Emmanuelle Jaillette and Florent Artru and Malika Balduyck},
  journal={Infectious disorders drug targets},
  year={2011},
  volume={11 4},
  pages={413-23}
}
Microaspiration of contaminated oropharyngeal secretions and gastric contents frequently occurs in intubated critically ill patients, and plays a major role in the pathogenesis of ventilator-associated pneumonia. Risk factors for microaspiration include impossible closure of vocal cords, longitudinal folds in high-volume low-pressure polyvinyl chloride cuffs, and underinflation of tracheal cuff. Zero positive end expiratory pressure, low peak inspiratory pressure, tracheal suctioning… CONTINUE READING
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