Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin.

Abstract

Heparin oligosaccharides derived by nitrous acid depolymerization of heparin have been immobilized on amine-coated glass slides. The formation of a Schiff base creates heparin chips that are a suitable platform for the high-throughput analysis of carbohydrate-protein interactions.

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Cite this paper

@article{Paz2006MicroarraysOH, title={Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin.}, author={Jos{\'e} L de Paz and Dorothe Spillmann and Peter H Seeberger}, journal={Chemical communications}, year={2006}, volume={29}, pages={3116-8} }