Microarrays for studying the host transcriptional response to microbial infection and for the identification of host drug targets.

@article{Yowe2001MicroarraysFS,
  title={Microarrays for studying the host transcriptional response to microbial infection and for the identification of host drug targets.},
  author={David Yowe and Walter J Cook and Jos{\'e} Carlos Guti{\'e}rrez-Ramos},
  journal={Microbes and infection},
  year={2001},
  volume={3 10},
  pages={813-21}
}
It is essential to understand the molecular basis of a host's response to microbial infection so that disease and tissue damage can be prevented. Modulation of host RNA expression is a critical set of molecular changes that occur upon infection. Global analysis of gene expression should provide an understanding of host RNA transcriptional changes that occur upon host-pathogen interaction. This series of articles focuses on the use of microarrays for analyzing the transcriptional response of a… CONTINUE READING