Microarrays (DNA chips) for the classroom laboratory.

@article{Barnard2006MicroarraysC,
  title={Microarrays (DNA chips) for the classroom laboratory.},
  author={B. Barnard and Michael Sussman and Sandra Splinter Bondurant and James Nienhuis and Patrick J. Krysan},
  journal={Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology},
  year={2006},
  volume={34 5},
  pages={355-9}
}
We have developed and optimized the necessary laboratory materials to make DNA microarray technology accessible to all high school students at a fraction of both cost and data size. The primary component is a DNA chip/array that students "print" by hand and then analyze using research tools that have been adapted for classroom use. The primary adaptation is the use of a simulated cDNA target. The low density DNA array we discuss here was used to demonstrate differential expression of several… CONTINUE READING

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