Microarray diagnosis of antibody-mediated rejection in kidney transplant biopsies: an international prospective study (INTERCOM).

@article{Halloran2013MicroarrayDO,
  title={Microarray diagnosis of antibody-mediated rejection in kidney transplant biopsies: an international prospective study (INTERCOM).},
  author={Philip F. Halloran and Aparecido Bernardo Pereira and Jessica P. Chang and Arthur J. Matas and Michael L. Picton and Denise de Freitas and Joan Bromberg and Daniel Ser{\'o}n and Jacobo Sellares and Gunilla Einecke and Jenna Reeve},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2013},
  volume={13 11},
  pages={
          2865-74
        }
}
In a reference set of 403 kidney transplant biopsies, we recently developed a microarray-based test that diagnoses antibody-mediated rejection (ABMR) by assigning an ABMR score. To validate the ABMR score and assess its potential impact on practice, we performed the present prospective INTERCOM study (clinicaltrials.gov NCT01299168) in 300 new biopsies (264 patients) from six centers: Baltimore, Barcelona, Edmonton, Hannover, Manchester and Minneapolis. We assigned ABMR scores using the… CONTINUE READING
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