Microarray data simulator for improved selection of differentially expressed genes.

@article{Singhal2003MicroarrayDS,
  title={Microarray data simulator for improved selection of differentially expressed genes.},
  author={Sunil Singhal and Chris G Kyvernitis and Steven W. Johnson and Larry Robert Kaiser and Michael N. Liebman and Steven M. Albelda},
  journal={Cancer biology & therapy},
  year={2003},
  volume={2 4},
  pages={383-91}
}
The development of microarray technology has allowed researchers to measure expression levels of thousands of genes simultaneously. Analysis of these data requires the best normalization and statistical approaches to account for the biological and technical variability inherent in the technique. To approach this problem we have developed a publicly available simulator of microarray hybridization experiments that can be used to help assess the accuracy of bioinformatic tools in discovering… CONTINUE READING

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