Microarray-based classification and clinical predictors: on combined classifiers and additional predictive value

@article{Boulesteix2008MicroarraybasedCA,
  title={Microarray-based classification and clinical predictors: on combined classifiers and additional predictive value},
  author={Anne-Laure Boulesteix and Christine Porzelius and Martin Daumer},
  journal={Bioinformatics},
  year={2008},
  volume={24 15},
  pages={1698-706}
}
MOTIVATION In the context of clinical bioinformatics methods are needed for assessing the additional predictive value of microarray data compared to simple clinical parameters alone. Such methods should also provide an optimal prediction rule making use of all potentialities of both types of data: they should ideally be able to catch subtypes which are not identified by clinical parameters alone. Moreover, they should address the question of the additional predictive value of microarray data in… CONTINUE READING