Microarray-based analysis: identification of hypoxia-regulated microRNAs in retinoblastoma cells.

@article{Xu2011MicroarraybasedAI,
  title={Microarray-based analysis: identification of hypoxia-regulated microRNAs in retinoblastoma cells.},
  author={Xiaofang Xu and Renbing Jia and Yixiong Zhou and Xin Ming Song and Jing Wang and Guanxiang Qian and Shengfang Ge and Xianqun Fan},
  journal={International journal of oncology},
  year={2011},
  volume={38 5},
  pages={1385-93}
}
Hypoxia is an essential feature of retinoblastoma and contributes to poor prognosis and resistance to conventional therapy. MicroRNAs (miRNAs) are small non-coding RNAs involved in a wide variety of biological processes, including cell differentiation, proliferation, death and metabolism. However, the relationship between hypoxia and the expression of miRNAs in retinoblastoma is not well understood. In this study, we aimed to analyze the pattern of miRNA expression in a retinoblastoma cell line… CONTINUE READING

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