Microarray analysis reveals pivotal divergent mRNA expression profiles early in the development of either compensated ventricular hypertrophy or heart failure.

  title={Microarray analysis reveals pivotal divergent mRNA expression profiles early in the development of either compensated ventricular hypertrophy or heart failure.},
  author={Henk P. J. Buermans and Everaldo M Redout and Anja Schiel and Ren{\'e} J. P. Musters and Marian J. Zuidwijk and Paul P. Eijk and Cornelis van Hardeveld and Soemini Kasanmoentalib and Frans C. Visser and Bauke Ylstra and Warner S. Simonides},
  journal={Physiological genomics},
  volume={21 3},
Myocardial right ventricular (RV) hypertrophy due to pulmonary hypertension is aimed at normalizing ventricular wall stress. Depending on the degree of pressure overload, RV hypertrophy may progress to a state of impaired contractile function and heart failure, but this cannot be discerned during the early stages of ventricular remodeling. We tested whether critical differences in gene expression profiles exist between ventricles before the ultimate development of either a compensated or… 

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