Microarray analysis reveals abnormal chromosomal complements in over 70% of 14 normally developing human embryos.

@article{Mertzanidou2013MicroarrayAR,
  title={Microarray analysis reveals abnormal chromosomal complements in over 70% of 14 normally developing human embryos.},
  author={Afroditi Mertzanidou and Leeanda Wilton and Joanne J Cheng and Claudia Spits and Evelyne Vanneste and Yves Moreau and Joris Robert Vermeesch and Karen Dora Sermon},
  journal={Human reproduction},
  year={2013},
  volume={28 1},
  pages={256-64}
}
STUDY QUESTION What are the aneuploidy rates and incidence of mosaicism in good-quality human preimplantation embryos. SUMMARY ANSWER High-level mosaicism and structural aberrations are not restricted to arrested or poorly developing embryos but are also common in good-quality IVF embryos. WHAT IS KNOWN ALREADY Humans, compared with other mammals, have a poor fertility rate, and even IVF treatments have a relatively low success rate. It is known that human gametes and early preimplantation… CONTINUE READING
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