Corpus ID: 36548999

Microarray analysis of retinal gene expression in Egr-1 knockout mice

@article{Schippert2009MicroarrayAO,
  title={Microarray analysis of retinal gene expression in Egr-1 knockout mice},
  author={Ruth Schippert and F. Schaeffel and M. Feldkaemper},
  journal={Molecular Vision},
  year={2009},
  volume={15},
  pages={2720 - 2739}
}
  • Ruth Schippert, F. Schaeffel, M. Feldkaemper
  • Published 2009
  • Biology, Medicine
  • Molecular Vision
    • Purpose We found earlier that 42 day-old Egr-1 knockout mice had longer eyes and a more myopic refractive error compared to their wild-types. To identify genes that could be responsible for the temporarily enhanced axial eye growth, a microarray analysis was performed in knockout and wild-type mice at the postnatal ages of 30 and 42 days. Methods The retinas of homozygous and wild-type Egr-1 knockout mice (Taconic, Ry, Denmark) were prepared for RNA isolation (RNeasy Mini Kit, Qiagen) at the… CONTINUE READING
    View on PubMed
    molvis.org
    18 Citations
    Highly Influencial Citations
    2
    Background Citations
    6
    Methods Citations
    2
    Results Citations
    1
    18 Citations
    Citation Type

    Citation Type

    Effects of Aging and Anatomic Location on Gene Expression in Human Retina
    • 22
    • PDF
    A profile of transcriptomic changes in the rd10 mouse model of retinitis pigmentosa
    • 22
    • PDF
    Gene profiling in experimental models of eye growth: Clues to myopia pathogenesis
    • 40
    • Highly Influenced
    Short term optical defocus perturbs normal developmental shifts in retina/RPE protein abundance
    • 4
    Pathway analysis identifies altered mitochondrial metabolism, neurotransmission, structural pathways and complement cascade in retina/RPE/ choroid in chick model of form-deprivation myopia
    • 4
    • PDF
    Gene-expression profiling to identify genes related to spontaneous tumor regression in a canine cancer model.
    • 16
    Anatomical differences of the protein profile in the rabbit sclera during growth
    • 2
    Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems
    • 61
    • Highly Influenced
    • PDF
    Investigating mechanisms of myopia in mice.
    • 48
    Early growth response factor-1 limits biliary fibrosis in a model of xenobiotic-induced cholestasis in mice.
    • 21
    • PDF

    References

    SHOWING 1-10 OF 71 REFERENCES
    Microarray analysis of retinal gene expression in chicks during imposed myopic defocus
    • 43
    • PDF
    Form-deprivation myopia in chick induces limited changes in retinal gene expression.
    • 62
    • PDF
    A microarray analysis of retinal transcripts that are controlled by image contrast in mice
    • 33
    Regulation of Egr-1, VIP, and Shh mRNA and Egr-1 protein in the mouse retina by light and image quality.
    • 37
    • PDF
    Relative axial myopia in Egr-1 (ZENK) knockout mice.
    • 80
    • PDF
    Ocular expression of avian thymic hormone: changes during the recovery from induced myopia
    • 23
    • PDF
    Temporal changes of novel transcripts in the chicken retina following imposed defocus.
    • 10
    • PDF
    Targeted inactivation of dystrophin gene product Dp71: phenotypic impact in mouse retina.
    • 137
    • PDF
    Visually induced changes in components of the retinoic acid system in fundal layers of the chick.
    • 68
    Retinoic Acid Increases in the Retina of the Chick with Form Deprivation Myopia
    • 65