Corpus ID: 36548999

Microarray analysis of retinal gene expression in Egr-1 knockout mice

  title={Microarray analysis of retinal gene expression in Egr-1 knockout mice},
  author={Ruth Schippert and F. Schaeffel and M. Feldkaemper},
  journal={Molecular Vision},
  pages={2720 - 2739}
  • Ruth Schippert, F. Schaeffel, M. Feldkaemper
  • Published 2009
  • Biology, Medicine
  • Molecular Vision
  • Purpose We found earlier that 42 day-old Egr-1 knockout mice had longer eyes and a more myopic refractive error compared to their wild-types. To identify genes that could be responsible for the temporarily enhanced axial eye growth, a microarray analysis was performed in knockout and wild-type mice at the postnatal ages of 30 and 42 days. Methods The retinas of homozygous and wild-type Egr-1 knockout mice (Taconic, Ry, Denmark) were prepared for RNA isolation (RNeasy Mini Kit, Qiagen) at the… CONTINUE READING
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