Microarray analysis of gene expression in adult retinal ganglion cells.

  title={Microarray analysis of gene expression in adult retinal ganglion cells.},
  author={Dmitry Ivanov and Galina Dvoriantchikova and Lubov Nathanson and Stuart James McKinnon and Valery I Shestopalov},
  journal={FEBS letters},
  volume={580 1},
Retinal ganglion cells (RGCs) transfer visual information to the brain and are known to be susceptible to selective degeneration in various neuropathies such as glaucoma. This selective vulnerability suggests that these highly specialized neurons possess a distinct gene expression profile that becomes altered by neuropathy-associated stresses, which lead to the RGC death. In this study, to identify genes expressed predominantly in adult RGCs, a global transcriptional profile of purified primary… CONTINUE READING


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