Microarray analysis of T-2 toxin-induced liver, placenta and fetal liver lesions in pregnant rats.

Abstract

Pregnant rats on day 13 of gestation were treated orally with 2 mg/kg of T-2 toxin and sacrificed at 1, 3, 6, 9 and 12 h after the treatment (HAT). Histopathologically, the number of apoptotic cells was increased in the liver, placenta and fetal liver (peaked at 6, 12 and 9-12 HAT, respectively). To examine the gene expression profiles, we performed… (More)

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Cite this paper

@article{Sehata2005MicroarrayAO, title={Microarray analysis of T-2 toxin-induced liver, placenta and fetal liver lesions in pregnant rats.}, author={Shinya Sehata and Naoki Kiyosawa and Fusako Atsumi and Kazumi Ito and Takashi Yamoto and Munehiro Teranishi and Koji Uetsuka and Hiroyuki Nakayama and Kunio Doi}, journal={Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie}, year={2005}, volume={57 1}, pages={15-28} }