Microarray analysis of Shigella flexneri-infected epithelial cells identifies host factors important for apoptosis inhibition

@article{Faherty2009MicroarrayAO,
  title={Microarray analysis of Shigella flexneri-infected epithelial cells identifies host factors important for apoptosis inhibition},
  author={C. Faherty and D. Merrell and C. Semino-Mora and A. Dubois and Aishwarya V Ramaswamy and A. Maurelli},
  journal={BMC Genomics},
  year={2009},
  volume={11},
  pages={272 - 272}
}
BackgroundShigella flexneri inhibits apoptosis in infected epithelial cells. In order to understand the pro-survival effects induced by the bacteria, we utilized apoptosis-specific microarrays to analyze the changes in eukaryotic gene expression in both infected and uninfected cells in the presence and absence of staurosporine, a chemical inducer of the intrinsic pathway of apoptosis. The goal of this research was to identify host factors that contribute to apoptosis inhibition in infected… Expand
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  • 7
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  • 17
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1
2
...

References

SHOWING 1-10 OF 113 REFERENCES
Shigella flexneri Inhibits Staurosporine-Induced Apoptosis in Epithelial Cells
  • 56
  • PDF
The Invasive Phenotype of Shigella flexneri Directs a Distinct Gene Expression Pattern in the Human Intestinal Epithelial Cell Line Caco-2*
  • 87
  • Highly Influential
  • PDF
A Bacterial Effector Targets Mad2L2, an APC Inhibitor, to Modulate Host Cell Cycling
  • 137
Molecular Pathogenesis of Shigella spp.: Controlling Host Cell Signaling, Invasion, and Death by Type III Secretion
  • 459
  • Highly Influential
  • PDF
A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.
  • 1,234
  • PDF
...
1
2
3
4
5
...