Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment.

  title={Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment.},
  author={Victoria E. Wagner and Daniel S. Bushnell and Luciano Passador and Andrew I. Brooks and Barbara H. Iglewski},
  journal={Journal of bacteriology},
  volume={185 7},
Bacterial communication via quorum sensing (QS) has been reported to be important in the production of virulence factors, antibiotic sensitivity, and biofilm development. Two QS systems, known as the las and rhl systems, have been identified previously in the opportunistic pathogen Pseudomonas aeruginosa. High-density oligonucleotide microarrays for the P. aeruginosa PAO1 genome were used to investigate global gene expression patterns modulated by QS regulons. In the initial experiments we… CONTINUE READING
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