Microarray analyses of the metabolic responses of Saccharomyces cerevisiae to organic solvent dimethyl sulfoxide

  title={Microarray analyses of the metabolic responses of Saccharomyces cerevisiae to organic solvent dimethyl sulfoxide},
  author={Weiwen Zhang and David L. Needham and Marie Coffin and April Rooker and Patrick Hurban and Matthew M. Tanzer and Jeffrey R. Shuster},
  journal={Journal of Industrial Microbiology and Biotechnology},
The toxic effects that organic solvents have on whole cells are important drawbacks in the application of these solvents in the production of fine chemicals by whole-cell stereoselective biotransformations. Although early studies found that organic solvents mainly destroyed the integrity of cell membranes by accumulating in the lipid bilayer of plasma membranes, the cellular metabolic responses to the presence of an organic solvent remain unclear. With the rapid development of genomics, it is… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 39 references

Genomic expression programs in the response of yeast cells to environmental changes

AP Gasch, PT Spellman, +5 authors PO Brown
Mol Biol Cell • 2000
View 5 Excerpts
Highly Influenced

Transcript abundance in yeast varies over six orders of magnitude.

The Journal of biological chemistry • 2002
View 1 Excerpt

Applications of DNA microarrays in microbial systems.

Journal of microbiological methods • 2001
View 1 Excerpt

Comprehensive identification of conditionally essential genes in mycobacteria.

Proceedings of the National Academy of Sciences of the United States of America • 2001
View 1 Excerpt

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