Microarray-Based Analysis of Methylation of 1st Trimester Trisomic Placentas from Down Syndrome, Edwards Syndrome and Patau Syndrome

@inproceedings{Hatt2016MicroarrayBasedAO,
  title={Microarray-Based Analysis of Methylation of 1st Trimester Trisomic Placentas from Down Syndrome, Edwards Syndrome and Patau Syndrome},
  author={Lotte Hatt and Mads Malik Aagaard and Cathrine Carlsen Bach and Jesper Graakjaer and Steffen Sommer and Inge Errebo Agerholm and S. Kolvraa and Anders Bojesen},
  booktitle={PloS one},
  year={2016}
}
Methylation-based non-invasive prenatal testing of fetal aneuploidies is an alternative method that could possibly improve fetal aneuploidy diagnosis, especially for trisomy 13(T13) and trisomy 18(T18). Our aim was to study the methylation landscape in placenta DNA from trisomy 13, 18 and 21 pregnancies in an attempt to find trisomy-specific methylation differences better suited for non-invasive prenatal diagnosis. We have conducted high-resolution methylation specific bead chip microarray… CONTINUE READING
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