MicroRNAs target gene and signaling pathway by bioinformatics analysis in the cardiac hypertrophy.

@article{Shen2010MicroRNAsTG,
  title={MicroRNAs target gene and signaling pathway by bioinformatics analysis in the cardiac hypertrophy.},
  author={E Shen and Xuehong Diao and Cong Wei and Zuohui Wu and Ling Zhang and Bing Hu},
  journal={Biochemical and biophysical research communications},
  year={2010},
  volume={397 3},
  pages={380-5}
}
Cardiac hypertrophy is a physiological adaptive response of the heart to diverse pathophysiological stimuli. Initially, it may be adaptive to normalize wall stress and to preserve contractile performance. This adaptive process may gradually progress to dilated cardiomyopathy, fibrotic diseases, arrhythmia, heart failure and even sudden death. Although various molecular pathways responsible for the coordinated control of the hypertrophic program, little is known about their underlying molecular… CONTINUE READING

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