MicroRNAs involved in chemo- and radioresistance of high-grade gliomas

@article{Besse2013MicroRNAsII,
  title={MicroRNAs involved in chemo- and radioresistance of high-grade gliomas},
  author={Andrej Besse and Jiri Sana and Pavel Fadrus and Ondrej Slaby},
  journal={Tumor Biology},
  year={2013},
  volume={34},
  pages={1969-1978}
}
High-grade gliomas (HGGs) are malignant primary brain tumors of glial cell origin. Despite optimal course of treatment, including maximal surgical resection followed by adjuvant chemo- and/or radiotherapy, the prognosis still remains poor. The main reason is the commonly occurring chemo- and radioresistance of these tumors. In recent years, several… CONTINUE READING