MicroRNAs in the regulation of immune cell functions--implications for atherosclerotic vascular disease.

@article{Zernecke2012MicroRNAsIT,
  title={MicroRNAs in the regulation of immune cell functions--implications for atherosclerotic vascular disease.},
  author={Alma Zernecke},
  journal={Thrombosis and haemostasis},
  year={2012},
  volume={107 4},
  pages={626-33}
}
Regarded as a chronic inflammatory disease of the vessel wall, the development of atherosclerotic lesions is shaped by immune responses and their regulation. Macrophages and dendritic cells are positioned at the crossroad of innate and adaptive immune responses by sensing atherogenic danger signals and by taking up and presenting antigens. T helper cells and auto-antibodies produced by B cells, together with their cytokine responses in turn modulate atheroprogression. In addition, platelets… CONTINUE READING

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