MicroRNAs in regulation of pluripotency and somatic cell reprogramming: small molecule with big impact.

Abstract

MicroRNAs (miRNAs), a group of small non-coding RNAs, have emerged as significant modulators in the establishment and generation of pluripotency, a developmental process that consists of complex cell-fate arrangements. The finding of embryonic stem cell (ESC) cycle-specific miRNAs reveals an important regulation scheme of pluripotency. Subsequent studies… (More)
DOI: 10.4161/rna.25828

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