MicroRNAs in pathogenesis of breast cancer: Implications in diagnosis and treatment.

Abstract

MicroRNAs (miRNAs) are small non-coding RNAs generated by a two-step complex process and are post transcriptional negative regulators of their target mRNAs. Dysregulation of many of these miRNAs has been associated with tumorigenesis in various cancers including breast cancer. Aberrantly high expression of specific miRNAs in breast cancer cells is… (More)
DOI: 10.5306/wjco.v5.i2.48

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