MicroRNAs in learning, memory, and neurological diseases.

  title={MicroRNAs in learning, memory, and neurological diseases.},
  author={Wenyuan Wang and Ester J. Kwon and Li-Huei Tsai},
  journal={Learning & memory},
  volume={19 9},
MicroRNAs (miRNAs) represent a class of small regulatory noncoding RNAs ∼22 bp in length that mediate post-transcriptional silencing of gene expression via the recognition of specific sequences in target messenger (m)RNAs. The current body of literature suggests that miRNAs are fine-tuning regulators of gene expression profiles in a wide range of biological processes, from development to cancer. Many miRNAs are highly expressed in the adult nervous system in a spatially and temporally… CONTINUE READING
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