MicroRNAs in kidney diseases: new promising biomarkers for diagnosis and monitoring.

@article{Schena2014MicroRNAsIK,
  title={MicroRNAs in kidney diseases: new promising biomarkers for diagnosis and monitoring.},
  author={Francesco Paolo Schena and Grazia Serino and Fabio Sallustio},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2014},
  volume={29 4},
  pages={
          755-63
        }
}
A series of microRNAs (miRNAs) have a critical role in many cellular and physiological activities such as cell cycle, growth, proliferation, apoptosis and metabolism. miRNAs are also important in the maintenance of renal homeostasis and kidney diseases. In vitro and in vivo animal models have shown a critical role of miRNAs in the development of diabetic nephropathy (DN) and in the progression of renal fibrosis. Specific miRNAs in renal tissue and peripheral blood mononuclear cells (PBMCs) are… CONTINUE READING

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