MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics

  title={MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics},
  author={Amanda A. Shea and Varsha Harish and Zainab Afzal and Juliet Chijioke and Habib Kedir and Shahnoza Dusmatova and Arpita Roy and Malathi Ramalinga and Brent C Harris and Jan K Blancato and Mukesh Verma and Deepak Kumar},
  booktitle={Cancer medicine},
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain, remaining incurable with a median survival time of only 15 months. In an effort to identify new targets for GBM diagnostics and therapeutics, recent studies have focused on molecular phenotyping of GBM subtypes. This has resulted in mounting interest in microRNAs (miRNAs) due to their regulatory capacities in both normal development and in pathological conditions such as cancer. miRNAs have a wide range of… CONTINUE READING
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