MicroRNAs in cancer.

  title={MicroRNAs in cancer.},
  author={Yong Sun Lee and Anindya Dutta},
  journal={Annual review of pathology},
Within the past few years, studies on microRNA (miRNA) and cancer have burst onto the scene. Profiling of the miRNome (global miRNA expression levels) has become prevalent, and abundant miRNome data are currently available for various cancers. The pattern of miRNA expression can be correlated with cancer type, stage, and other clinical variables, so miRNA profiling can be used as a tool for cancer diagnosis and prognosis. miRNA expression analyses also suggest oncogenic (or tumor-suppressive… CONTINUE READING