MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis.

@article{Kren2009MicroRNAsII,
  title={MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis.},
  author={Betsy T. Kren and Phillip Y-P Wong and Aaron L. Sarver and Xiao-xiao Zhang and Yan Zeng and Clifford J. Steer},
  journal={RNA biology},
  year={2009},
  volume={6 1},
  pages={65-72}
}
MicroRNAs (miRNAs) are a class of small approximately 22 nt noncoding (nc) RNAs that regulate gene expression post-transcriptionally by direct binding to target sites on mRNAs. They comprise more than 1,000 novel species in mammalian cells and exert their function by modulating gene expression through several different mechanisms, including translational inhibition, and/or degradation of target mRNAs. Mitochondria maintain and express their own genome, which is distinct from the nuclear… CONTINUE READING
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